Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: That is an impurity related to bortezomib, a proteasome inhibitor used in the therapy of several myeloma. Its synthesis or study is very important for guaranteeing the purity and safety with the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor within the synthesis of abiraterone acetate, a drug Utilized in the cure of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-one): A essential compound within the synthesis of imatinib, a drug that targets specific different types of cancer, together with Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats many cancers including breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are definitely intermediates while in the synthesis of gemcitabine, an anti-most cancers drug. Their research is crucial for optimizing the generation approach and making sure large purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is utilized to deal with breast most cancers, and these intermediates are involved in its creation.
Fulvestrant Intermediates: Fulvestrant is an estrogen receptor antagonist Employed in the remedy of CAS NO. 314771-76-1 breast most cancers. Numerous intermediates assist in the synthesis of the drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug productive in managing cancers including ovarian, breast, and lung most cancers.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the cure of colorectal most cancers and small cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-nine): This compound is involved CIS-3-HYDROXY-4-PHENYL-2-AZETIDINONE in the synthesis of adamantane derivatives, which have many applications, including antiviral Attributes.
Vildagliptin Intermediates: Employed in the production of vildagliptin, an oral drug for style two diabetes that inhibits the enzyme DPP-four to control blood sugar levels.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved in the synthesis of various gluconic acid derivatives, that are Employed in meals, pharmaceutical, and industrial apps.
Canagliflozin Intermediate 2: A precursor while in the synthesis of canagliflozin, a medication utilised to control variety two diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).